Array-based services include gene expression profiling on 3' arrays, Exon 1.0 ST arrays, and on Gene 1.0 ST arrays; genotyping and comparative genomic hybridization both on single nucleotide polymorphism (SNP) arrays, and Chromatin ImmunoPrecipitation localization (ChIP-on-Chip) on tiling arrays. All services use oligonucleotide microarrays. Next Generation Sequencing (NGS) services include DNA-based and RNA-based applications. Biostatistical support to assist in analyzing the data is available. The services of the Core are accessible to DFCI investigators and to investigators outside of DFCI.

Laboratory

The laboratory analyses begin with RNA or DNA, provided by investigators, and produce scan data (microarrays) or sequence data (NGS) along with quality control data. These data are available via password-protected accounts accessible through this web site.

Biostatistics

Biostatistical Support is available at the facility to educate investigators about approaches and tools for microarray and NGS data analysis. Assistance with concepts and software.

Pricing

Instrumentation, computers and other start-up costs have been provided by the generosity of donors. The pricing structure for laboratory analyses consists of two tiers - one for DFCI investigators, and another for investigators outside of DFCI.